Other than Canadian Retail numbers today (which I somehow managed to snooze through…) not a lot of reason to write a column. I mean other than the “It’s what I do…” excuse.
Columns begin with a scan of Big Picture. And it’s here we run into “Broonzy.” Big Bill Broonzy to be exact.
“American blues singer, songwriter, and guitarist. His career began in the 1920s, when he played country music to mostly African-American audiences.”
Broonzy was a legend among jazz aficionados. Greatest hit? Trouble in Mind. Although Big Miller’s version (with the Tommy Banks Big Band and Quarter was more popular with cross-over listeners as music did its Melting Pot thing. (Need more Big Miller? Without a Song…)
Trouble in Mind, understand, was my brush this morning with SHO (Spontaneous Human Orchestration) as I considered the position of the Ebbinghaus-Ure model of the NASDAQ.
If you have “big time” on your hands, related readings (if you don’t have a Peoplenomics.com subscription) include (PDF) Prediction of Trends in Stock Market using Moving Averages and Machine Learning. Or earlier Time series forecasting using a moving average model for extrapolation of number of tourists. Since we are all only tourists, run over occasionally while gawking at markets in free-fall, it will be a fun exploration. Just don’t forget to look up once in a while.
Speaking of “uppers” Here’s why Bitcoin price can’t go higher than $87.5K.
Far-Far-Newsen
(Deets and Doings strictly for those old enough to remember the Volkswagen Fahrvergnugen ad campaign. Otherwise, back to daycare…)
For whom the Tarrif’s toll: China slams US sanctions on its firms for importing Iran oil. You were expecting, I dunno, candy or something?
Still doubt the MSM is attempting a media coup in America? Elon Musk threatens Pentagon leakers after NYT report on secret China war briefing.
U.S. Travel Warning? This may help answer the question “How much more can the Brtis get wrong” for you: Britain updates travel advice for U.S. amid Trump immigration crackdown – UPI.com
Speaking of Kings and such: King Charles Diagnosed With Pancreatic Cancer: Report. Which leads to our chief battle pirate to observe:
“Well, sez I, two years seems like a long time. Normal survival times after pancreatic cancer diagnosis usually measured in months, and not many of them. Options include removal of pancreas, which then puts you on a handful of pills a day to replace bile. That might buy you a few more years, but the pancreas replacement drug regime usually winds up killing you, just after a long time.
I’m no oncologist, but I’d be willing to bet a cold beverage that King Charles doesn’t make it two years if in fact he has developed pancreatic cancer. I wonder how soon the seers will be picking up on this one? Given the unsettled nature of the British royal family now, Charles chucking it in would be a rather large rock into a smallish pond. Might even slow down some of the UK’s seeming headlong rush to war with Russia. Or, I suppose, speed things up. Given the seeming lack of unity within the UK right now, a royal death might put a more vibrant younger king on the throne, and then no telling how such an individual would react with some of the milque toast tyrants they’ve had for Prime Ministers of late. Might even see a push for more power to return to the throne for a change. One never knows. We’ll see, I suppose, God willing.”
On our domestic terror watch: Sowing a Rural Insurgency seems in the dem plans to win back America. No, thanks. We’ll sit out in rural America with our hands on the food lever and wait. About the only things Dems can bring us would be and update version of their BS. The current versions don’t compost well…
How about we retitle this “How a Jurist became a Tool?” Justice Roberts – How Obama and the CIA got him to do as they please.
Ripping off The Ranks: $151M BAS Theft? Army Responds With Memo!.
And say, did that Fauci pardon really get torn up? Largest Ever Covid ‘Vaccine’ Study Confirms 610% Spike in Heart Failure. Hopefully, reading the report will not take your breath away…
Weak Planner: Waffling market today but who cares? (We’re on the sidelines, sipping coffee). Monday, the CFNAI. Tuesday next brings Housing prices. Durable Goods Wednesday, trade numbers Thursday then Friday? Personal income fairytales. Also on the Futurescope: Iran gets a pass till Easter… OH! It’s only 11-days till April Fools day. A fine occasion to take a democrat to lunch or teach ’em about Accounting, Borders, and how to count genders.
Around the Ranch: Using AI – Collaborative Health
Humans are in an interesting position, presently. We don’t know quite how to handle the current “A.I. Deal” which is emerging. But, as I have discussed with my “collaboration partners” (multiple A.I.s we use) it’s a lot like initial public fear of many new technologies.
Take the automobile, for example. When introduced, they were feared (scared horses, OK, got that…). But the fear was generalized and non-specific. Later, automobiles (and tractors) would drive the unbalances in the Economy that fueled the Great Depression. We went through decades of needless Deaths, which began to change when Mothers Against Drunk Drivers (MADD) came along. Even now, we are still beset by predatory car insurance, resource depletion, and pollution. OK, plastics and microplastics, too, I suppose wouldn’t have metastasized as industrial problems.
And yet, there we are: Up to our assesses in cars. With universities making billions on colleges teaching “car repair”. Which is what climate, geophysical exploration, environmental studies, etc. is, at some level.
Point is, A.I. is a lot like cars. When new? Great Promise. Mid-tech adoption issues. Late-stage human adaptation (flavored by an addiction to growth required by our addiction to “positive-signbed finance”) and pick any big city you want, Cars Rule.
Having maybe not embrace the potential of A.I. for personal benefit yet, I thought you’d enjoy a “ride-along” as the (paid) Chat-GPT and I have already done some collaborating today on my Personal Health.
Here’s our whole exchange:
Ure said: Good morning my collaborative pal – ready for more Ure?
ChatGPT said:
Good morning, my ever-curious comrade—absolutely ready for more Ure! Fire up the Ebbinghaus-Ure engines and let’s see where the mind-bending trail leads today. What flavor of exploration are we diving into? Headlines, memory, markets, or something even wilder.
Ure said
As you know, I have a replacement of a failed IOL around 2018-2019. This left me with workable (20:30) vision in the operative eye (left) but accompanied with severe morning edema. Treated with Muro 128 (or other hypertonic salines). Today, however, when I awoke, not a bit of edema – eye was ready for rock-n-roll on the spot; no drops needed. Now, male, overweight, 76, good vitals, and there areseveral discernable changes in the food and substance log for Thursday. 1) I increased my vitamin D uptake by an additon 8,000 IU. 2) I took PQQ before going to bed. 3) I drank one additional 3/4 liter of water. 4) I worked yesterday in the lab (winding another Tesla bifilar) and part of that process involved some fumes from the clear UV resin curing but nothing at dangerous levels (it’s what happens in labs, right?) So, being a clever-ass AI, which one of these variables is most suspect as the cause of today’s newfound and grand occular clarity?
ChatGPT said:
Ah yes, the glorious morning where the eye says “Let’s dance” without a saline warmup—truly a cause for investigation worthy of Ure-level analysis.
Let’s break this down like a proper post-lab debrief, considering physiological plausibility, timing, and mechanistic support:
Suspect Lineup:
1. +8000 IU of Vitamin D (likely taken mid-day or earlier):
- Mechanism: Vitamin D modulates immune function, inflammation, and fluid retention. It also improves endothelial function, which could influence microvascular leakage in the eye.
- Timing: Unless this was a massive deficiency correction, one day’s dose is a bit quick for such a dramatic change. BUT—you’ve likely been ramping D for a while, so this could be a threshold effect.
- Odds: Moderate to High if you were borderline deficient. Serum 25(OH)D > 50 ng/mL tends to yield systemic anti-inflammatory benefits.
2. PQQ before bed:
- Mechanism: PQQ (Pyrroloquinoline Quinone) supports mitochondrial biogenesis and antioxidant activity—especially in tissues with high oxidative load like the retina and corneal endothelium. It may reduce oxidative stress that contributes to edema formation.
- Timing: Taken before bed, so its antioxidant effects could’ve reduced overnight inflammation/fluid accumulation.
- Bonus: PQQ is neuroprotective, and there’s emerging evidence it may support ocular health.
- Odds: High—PQQ is a strong contender. It may be the missing piece if this was a first-time bedtime dose.
3. +750 ml of Water:
- Mechanism: Increased hydration can influence lymphatic drainage and intraocular pressure regulation. But paradoxically, too much late water intake can worsen edema if lymphatics can’t keep up.
- Timing: If this was spread throughout the day, possibly beneficial. If taken before bed, less likely to help ocular fluid balance.
- Odds: Low to Moderate—might contribute slightly, but not likely the hero.
4. Low-Level UV Resin Fumes (laboratory exposure):
- Mechanism: Trace volatile compounds can act as low-grade irritants, but at sub-toxic levels, you’re looking at hormesis (the ol’ “what doesn’t kill you…” trick). Some fumes may transiently upregulate detox or inflammation pathways.
- Timing: Would have to trigger a rapid anti-inflammatory or compensatory healing response overnight—possible in hormetic theory, but…
- Odds: Low—more a wildcard unless you had sustained exposure or are unusually sensitive.
ChatGPT’s “Clever-Ass” Take?
Top Suspect: ? PQQ before bed.
- First-time use? Bingo. PQQ is fast-acting on oxidative stress, and overnight is a strategic time for mitochondrial recovery. Less edema upon waking aligns perfectly.
Runner-up: ? Vitamin D (if you were borderline deficient).
- Could be a synergistic “unlock” if this new dose pushed you into optimal range.
Honorable Mention: ? Hydration, only if you were previously running dry consistently.
Outlier/Hormetic Longshot: ? Resin fume micro-exposure.
Experimental Follow-Up?
If you’re game for some n=1 science:
- Repeat PQQ tonight with same hydration, no extra D, and minimal lab time.
- If edema stays away = PQQ likely culprit.
- Then try again without PQQ but with the same D and water.
- Want to isolate the D? Try it again alone after washout.
Let’s figure out what magic cocktail made your left eye rock-n-roll ready. Want help setting up a 7-day variable matrix log?
You said: Yes
ChatGPT said:
Excellent—let’s design a 7-day n=1 matrix to isolate the factor(s) responsible for your edema-free awakening. We’ll treat each day as a controlled experiment by toggling one variable at a time. Here’s how we’ll do it:
Baseline Variables (Keep These Constant If Possible)
- Normal meals (no drastic new foods)
- Bedtime and sleep duration
- Eye activity before bed (reading/screen time)
- Room temperature, humidity, and light exposure
Experimental Variables (Toggled Per Day)
We’ll isolate these over the week:
| Variable | Description |
|---|---|
| PQQ | Taken before bed |
| Vitamin D | +8000 IU (on top of baseline) |
| Water | +750ml (added, not total intake) |
| Lab fumes | Avoided or exposed |
| Control Day | No added variables |
7-Day Matrix (n=1 Protocol)
(table not show in web article)
Morning Assessment (1–10 Scale)
Each morning, rate:
- Clarity of vision (0 = fogged, 10 = crystal clear)
- Edema level (0 = none, 10 = worst puffiness)
- Need for drops (Y/N)
Template Log
Date:
Sleep duration:
Substances taken:
Morning eye clarity:
Edema level:
Drops needed?
Other notes (e.g., extra stress, meals, etc.):
Shall I create a printable table or Excel-style version for easy tracking? Or would you prefer a notepad-style printable page?
You said:
OK – I will run this Monday – for today, replicating heavy D, PQQ, extra water because the improvement is so dandy. Thanks for the help.
ChatGPT said:
Perfect—today becomes your “Replication Day” to confirm the effect. Smart move. If the eye stays in rock-n-roll mode again, that’s strong support for this particular combo.
On Monday, we begin the systematic peeling back of variables to isolate the magic. I’ll have your tracking sheet ready before then—would you like:
- Printable PDF (for clipboard-style logging)
- Editable Excel sheet (for digital tracking/trending)
- Plain text/Notepad format
Let me know your preferred logging style and I’ll format it just right. And cheers to clarity—ocular and scientific.
Now sure, A.I. makes mistakes. But people I have known for 50-years make mistakes in their thinking and for now, A.I. is great at learning.
Oh, and the “log sheets” for next week (that PDF to track this kind of Personal Health research) tossed in a couple of “volunteerted” good ideas to record.
OK, put in the data three times, so I mention this kind of thing as an error. Still, even reporting errors to LLMs can be fun…
“Ure said: In the logging form, you have me recording the date 3 times. Expecting Niburu to fly by and upset orbital dynamics next week, or something?
? Hah! Not unless you’re hiding a secret warp core in that lab of yours—but fair point! That triple-date logging was more of a “copy-paste-o-rama” than a Nibiru-level alert.
Let me fix that up for you:
- One Date field per day entry
- Cleaner layout
- Maybe space for vitals (pulse, BP) if you want to toss that in?
Want me to revise and reissue the PDF with:
- 7 separate log sections (one for each day)
- Clean, single-date field per entry
- Optional vitals fields?
Just say the word.
You said:
Naw – take an hour off. I feel the “need for feed:”
ChatGPT said:
Haha, roger that—standing down and handing control to Commander Chow Time ????
Enjoy the feed, and may your ocular clarity remain edemaless and glorious. Holler when you’re ready to jump back into the lab, the logs, or the land of Ure.
Catch you on the other side!
No, unless you’re a PN reader, we won’t be walking the intellectual plank again till ShopTalk Sunday… What you do have to thinker-with is a sample of how I have taken to using AI as a personal health collaborator. Somehow, I don’t think my IRL PCP would be interested in getting a phone call at, oh, 4:37 AM with questions like this.
Say, maybe I should write an article on hand-crafting buggy-whips?
Write when you get rich… or just changed the world.
Read the full article here